General Information

  • ID:  hor002493
  • Uniprot ID:  NA
  • Protein name:  Citropin 11
  • Gene name:  NA
  • Organism:  Litoria lesueurii
  • Family:  NA
  • Source:  Animal
  • Expression:  skin glands
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  GLFDVIKKVASVIGGL
  • Length:  16
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T16 Leucine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Be smooth muscle active and analgaesic
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002493_AF2.pdbhor002493_ESM.pdb

Physical Information

Mass: 188373 Formula: C76H130N18O20
Absent amino acids: CEHMNPQRTWY Common amino acids: GV
pI: 9.54 Basic residues: 2
Polar residues: 4 Hydrophobic residues: 9
Hydrophobicity: 128.13 Boman Index: 1619
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 158.13
Instability Index: 1418.75 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  11784303
  • Title:  Amphibian Peptides That Inhibit Neuronal Nitric Oxide Synthase. Isolation of Lesuerin From the Skin Secretion of the Australian Stony Creek Frog Litoria Lesueuri